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Puppy Vaccination Schedule: Complete Guide

Flovvi Team


Puppies need a series of vaccinations starting at 6–8 weeks of age to build protection against life-threatening diseases before their maternal antibodies fade. Missing or delaying vaccines leaves a puppy vulnerable during one of the highest-risk periods of its life.

## Why Puppies Need a Series of Shots

Puppies are born with some immunity passed from their mother through colostrum (first milk). This maternal antibody protection fades between 6 and 16 weeks. Until it fully fades, it also interferes with vaccines β€” meaning a single early vaccine may not produce lasting immunity. A series ensures at least one shot lands after maternal antibodies have declined enough.

## Core Vaccines (Every Puppy Needs These)

Distemper, Parvovirus, Adenovirus (DAP / DHPP)
The most critical combination. Parvovirus kills up to 91% of unvaccinated puppies if untreated; distemper leaves survivors with lasting neurological damage.

Rabies
Required by law in most countries. Given at 12–16 weeks.

## Recommended Schedule

| Age | Vaccines |
|-----|---------|
| 6–8 weeks | DAP (first dose) |
| 10–12 weeks | DAP (second dose) + Leptospirosis (first dose) |
| 14–16 weeks | DAP (third dose) + Leptospirosis (second dose) + Rabies |
| 12–16 months | DAP booster + Rabies booster |

## Non-Core Vaccines (Based on Risk)

- Leptospirosis β€” recommended for dogs with outdoor/water access; given as part of standard UK/EU protocols
- Kennel Cough (Bordetella + Parainfluenza) β€” essential for dogs attending kennels, dog parks, or training classes
- Lyme disease β€” recommended in endemic tick regions

## After the Final Puppy Shot

Keep your puppy away from unvaccinated dogs and environments where unknown dogs have been until 1–2 weeks after the final puppy vaccination. The immune system needs this time to build full protection.

Schedule appointments in Flovvi β€” set reminders for each booster so you never miss a dose.

When to see a vet

Consult your vet if your puppy shows lethargy, vomiting, or loss of appetite within 24–48 hours of vaccination. Seek immediate care if there is facial swelling or difficulty breathing (rare allergic reaction).

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Updated: 25/05/2026

Reviewed by the Flovvi Veterinary Team

Puppy Vaccination Schedule: Complete Guide | Flovvi | Flovvi